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Guidance

Complete routine immunisation schedule from 1 January 2026

Updated 3 March 2026

Routine immunisation programmes

Age due Diseases that vaccines protect against Vaccine given Trade name Usual site [footnote 1]
8 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B
DTaP/IPV/Hib/HepB (6 in 1 vaccine) Infanrix hexa or Vaxelis Thigh
Ìý Meningococcal group B (MenB) MenB Bexsero Thigh
Ìý Rotavirus gastroenteritis Rotavirus Rotarix [footnote 2] By mouth
12 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B DTaP/IPV/Hib/HepB (6 in 1 vaccine) Infanrix hexa or Vaxelis Thigh
Ìý MenB MenB Bexsero Thigh
Ìý Rotavirus Rotavirus Rotarix [footnote 2] By mouth
16 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B DTaP/IPV/Hib/HepB (6 in 1 vaccine) Infanrix hexa or Vaxelis Thigh
Ìý Pneumococcal (13 serotypes) PCV Prevenar 13 Thigh
One year old (on or after the child’s first birthday) Pneumococcal PCV Prevenar 13 Upper arm or thigh
Ìý Measles, mumps, rubella and varicella (chickenpox) MMRV ProQuad or Priorix Tetra Upper arm or thigh
Ìý MenB
MenB Bexsero Upper arm or thigh
18 months old Born on or after 1 July 2024
DTaP/IPV/Hib/HepB.
Measles, mumps, rubella and varicella
Born on or before 30 June 2024
No appointment
DTaP/IPV/Hib/HepB
MMRV
Infanrix hexa or Vaxelis
ProQuad or Priorix Tetra
Upper arm or thigh
3 years, 4 months old or soon after Born on or after 1 January 2025
Diphtheria, tetanus, pertussis and polio
Born on or before 31 December 2024
Diphtheria, tetanus, pertussis and polio.
Measles, mumps, rubella and varicella
dTaP/IPV
MMRV
REPEVAX
ProQuad or Priorix Tetra
Upper arm or thigh
Boys and girls aged 12 to 13 years Cancers and genital warts caused by specific human papillomavirus (HPV) types HPV Gardasil 9 Upper arm
14 years old (school Year 9) Tetanus, diphtheria and polio Td/IPV REVAXIS Upper arm
Ìý Meningococcal groups A, C, W and Y MenACWY MenQuadfi Upper arm
65 years old Pneumococcal (23 or 20 serotypes) Pneumococcal polysaccharide vaccine (PPV23) or Pneumococcal conjugate vaccine (PCV20) once PPV23 stock exhausted Pneumovax 23 or Prevenar 20 Upper arm
65 years of age and older Influenza (each year from September) Inactivated influenza vaccine Multiple Upper arm
Individuals turning 65 from 1 Sept each year
(commencing 1 Sept 2023 onwards)
Shingles Shingles vaccine Shingrix Upper arm
70 to 79 years of age
(and those severely immunosuppressed over 18 years of age)
Shingles Shingles vaccine Shingrix Upper arm
75 years of age Respiratory syncytial virus (RSV) RSVÌývaccine Abrysvo Upper arm
Eligible paediatric age group
See annual flu letter
Influenza (each year from September) LAIV (Live attenuated influenza vaccine)
– if LAIV is contraindicated or otherwise unsuitable, use inactivated flu vaccine (check Green Book chapter 19 for details)
Fluenz (contains porcine gelatine) Both nostrils

Selective immunisation programmes

Target group Age and schedule Disease Vaccines required
Babies born to women with hepatitis B infection Ìý[note 1],Ìý[note 2] At birth, 4 weeks
if born before 1 July 2024 give additional dose at 12 months oldÌý[note 1]
Hepatitis B Hepatitis B (Engerix B/HBvaxPRO) Ìý
Infants in areas of the country with tuberculosis (TB) incidence at least 40 per 100,000 Around 28 days oldÌý[note 4] Tuberculosis BCG Ìý
Infants with a parent or grandparent born in a high incidence countryÌý[note3] Around 28 days oldÌý[note 4] Tuberculosis BCG Ìý
Children in a clinical risk group Age under 2 years
• if first ever flu vaccine give second dose at 4 weeks
Influenza inactivated flu vaccine Ìý
Ìý Age under 2 years
• if first ever flu vaccine give second dose at 4 weeks
Influenza LAIVÌýor inactivated flu vaccine if contraindicated toÌýLAIVÌý Ìý
Ìý Age 9 to 17 years
• one dose required each flu season
Influenza LAIVÌýor inactivated flu vaccine if contraindicated toÌýLAIVÌý Ìý
Pregnant women At any stage of pregnancy during flu season Influenza Inactivated flu vaccine Ìý
Ìý From 16 weeks gestationÌý[note 5] Pertussis TdapÌý(ADACEL) Ìý
Ìý From 28 weeks gestation RSV RSVÌývaccine (Abrysvo) Ìý

Notes


Note 1. Take blood for HBsAg on or after 12 months to exclude infection. For children born on or after 1 July 2024, test anytime between 12 and 18 months.
Note 2. In addition hexavalent vaccine (Infanrix hexa or Vaxelis) is given at 8, 12 and 16 weeks and, for children born on or after 1 July 2024, also at 18 months.
Note 3. Where the annual incidence of TB is 40 per 100,000 or higher – see TB incidence by country.
Note 4. Check SCID screening outcome before giving BCG.
Note 5. Ideally before 32 weeks gestation but may still be given after 32 weeks.

Additional vaccines for individuals with underlying medical conditions

Medical condition Diseases protected against Vaccines requiredÌý[note 1]
Asplenia or splenic dysfunctionÌý
(this also includes individuals with coeliac disease who are diagnosed with splenic dysfunction and all haemoglobinopathies including homozygous sickle cell disease)
Meningococcal groups A, B, C, W and Y MenACWY
MenB
Ìý Pneumococcal PCV13Ìý(up to 10 years of age)Ìý[note 2]
PPV23 (from 2 years of age)
Ìý Influenza Annual flu vaccine
Cochlear implants Pneumococcal PCV13Ìý(up to 10 years of age)Ìý[note 2]
PPV23 (from 2 years of age)
Chronic respiratory and heart conditionsÌý(such as severe asthma, chronic pulmonary disease, and heart failure) Pneumococcal PCV13Ìý(up to 10 years of age) [note 2]
PPV23 (from 2 years of age)
Ìý Influenza Annual flu vaccine
Chronic neurological conditions Pneumococcal (only if the individual is also at increased risk of aspiration) PCV13Ìý(up to 10 years of age)Ìý[note 2]
PPV23 (from 2 years of age)
Ìý Influenza Annual flu vaccine
Diabetes Pneumococcal PCV13Ìý(up to 10 years of age)Ìý[note 2]
PPV23 (from 2 years of age)
Ìý Influenza Annual flu vaccine
Chronic kidney disease (CKD)Ìý(including haemodialysis) Pneumococcal (stage 4 and 5ÌýCKD) PCV13Ìý(up to 10 years of age)Ìý[note 2]
PPV23 (from 2 years of age)
Ìý Influenza (stage 3, 4 and 5ÌýCKD) Annual flu vaccine
Ìý Hepatitis B (stage 4 and 5ÌýCKD) Hepatitis B
Chronic liver conditions Pneumococcal PCV13Ìý(up to 10 years of age)Ìý[note 2]
PPV23 (from 2 years of age)
Ìý Influenza Annual flu vaccine
Ìý Hepatitis A Hepatitis A
Ìý Hepatitis B Hepatitis B
Haemophilia Hepatitis A Hepatitis A
Ìý Hepatitis B Hepatitis B
ImmunosuppressionÌýdue to disease or treatmentÌý[note 4] Pneumococcal PCV13Ìý(up to 10 years of age)Ìý[note 2] [note 3]
PPV23 (from 2 years of age)
Ìý Shingles vaccine Shingrix – from 18 years of ageÌý[note 5]
Ìý Influenza Annual flu vaccine
Complement disordersÌý(including those receiving complement inhibitor therapy) Meningococcal groups A, B, C, W and Y MenACWY
MenB
Ìý Pneumococcal PCV13Ìý(up to 10 years of age)Ìý[note 2]
PPV23 (from 2 years of age
Ìý Influenza Annual flu vaccine

Notes


Note 1. Check relevant chapter of the Green Book for specific schedule.
Note 2. If aged 2 years to under 10 years of age and unimmunised or partially immunised against pneumococcal infection, give one PCV13 dose.
Note 3. To any age in severely immunosuppressed.
Note 4. Consider annual influenza vaccination for household members and those who care for people with these conditions.
Note 5. Check Green Book Shingles Chapter 28a.

  1. Intramuscular injection into deltoid muscle in upper arm or anterolateral aspect of the thigh.Ìý↩

  2. Rotavirus vaccine should only be given after checking for SCID screening result.Ìý↩Ìý↩2